Misses next match if booked: Gianluca Zambrotta, Luca Antonini, Kevin-Prince Boateng, Mathieu Flamini (all Milan)
Match facts
Tottenham, the only Champions League debutant still in the competition, have scored 14 goals at home in their four games, including the qualifying round, and have conceded just two.
Tottenham's Cameroon full-back Benoit Assou-Ekotto is one of only 15 players in this season's competition to have started and finished all his club's seven Champions League games.
Dutch forward Rafael van der Vaart has scored twice for Tottenham in four Champions League appearances since joining the club this season. That ended a drought of 10 games without a goal in the competition when he was with Real Madrid. Before signing for Real, he scored three goals in three Champions League matches for Hamburg.
Milan have won just once in 14 away games in England, a 1-0 victory over Manchester United at the same stage of the competition six years ago. They have lost nine, the last a 4-0 defeat in the same round last season, also against United.